The main etiology and pathogenesis of rhinitis

Now the number of young people suffering from rhinitis was a straight line in the rise, more and more young people suffering from rhinitis caused by adverse reactions and life of the cumbersome, discomfort. What is the origin of rhinitis for us, why are we infected with rhinitis?
First, the cause:

In the healthy state, the following can be detected in the following pathogens, such as Staphylococcus epidermidis, Staphylococcus aureus, pseudo-diphtheria bacillus, Gram-negative bacteria, coagulase-negative staphylococcus Streptococcus sp., Hemolytic streptococcus, micrococcus; anaerobic bacteria with Propionibacterium, Pseudomonas, anaerobic bacteria, Fusobacterium and Streptococcus digestion; there are a small amount of fungi Haemophilus, pneumococcus, Staphylococcus aureus, Gram-negative bacilli and Neisseria meningitidis. Healthy children are found in the nasal passages for the typical pathogens: Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae.
Under normal circumstances, nasal detoxification function to ensure that the bacteria do not exceed the number of people can bear. In case of predisposing factors such as cold, rain, fatigue, nasal detoxification function, the bacteria can stay in the nasal cavity for a long time and a large number of breeding, and then lead to colds. Cold inflammation for a long time is easy to deteriorate to rhinitis.
Second, the pathogenesis:
There is a family history of allergic disease susceptible to the disease. Patient family with more asthma, urticaria or drug allergy history. In the past, this patient is an atopic individual, and its ability to produce IgE antibodies in vivo is higher than normal. But in recent years, the authors found that there was no significant difference between the twin and the general population.
The susceptibility is due to the frequent stimulation of the antigenic substance, but its susceptibility is the ability of the mast cells, the number of basophils and the ability to release the chemical medium in the nasal mucosa. It has been confirmed that the number of cells in the nasal mucosa of patients with allergic rhinitis is not only higher than that of normal people, but also has a strong ability to release chemical mediators.
The antigenic substances that stimulate the body to produce IgE antibodies are called allergens. The allergen material once again into the nasal mucosa and the corresponding IgE binding caused by allergic reactions. Cause the disease of the allergen according to its way into the human body is divided into two categories of inhalation and food:
Inhalation allergens
Breathe in the nasal cavity by breathing. Such allergens are mostly suspended in the air.
(1) pollen is not all plant pollen can cause disease. Only those pollen large, wide vegetation area, allergenic and with the wind
The pollen is most likely to become an allergen. Due to the differences in vegetation varieties, pollen with allergenicity in different areas is also different.
(2) fungi are widely distributed in nature, mainly in soil and corrupt organic matter. The hyphae and spores are allergenic, but with strong spores.
(3) house dust mite arthropod door spider gang. Adult size is generally 300 ~ 500μm. Mainly parasitic in every corner of the room, which mattresses, pillows, sofa mats, etc. in the most dust. Mite excrement, eggs, scaling and its broken body, can become allergens.
(4) animal dander animal dander is one of the strongest allergens.
For susceptible individuals if the long-term contact with the animals concerned, can be sensitized. Even after a small amount of deodorization, but also to stimulate the nose symptoms.
(6) indoor dust is caused by perennial rhinitis one of the common allergen substances. Its composition is quite complex, is a variety of substances hodgepodge, including animal, plant and chemical and other substances.
Incubate allergen
Refers to the digestive tract into the human body caused by nasal symptoms of allergen substances. Its role in the nasal mucosa is very complex, it is still not clear, milk, eggs, fish, meat, fruit, and even some kind of vegetables, can become allergens.
So in the usual life we ​​should not only pay attention to the maintenance of personal health, the same should also be away from the allergens that may cause rhinitis, so I believe that infection rhinitis is already going to be the past.